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Verse 21

You, being in past times alienated and enemies in your mind in your evil works,

Referenced Verses

Eph 2:12 : 12 that you were at that time separate from Christ, alienated from the commonwealth of Israel, and strangers from the covenants of the promise, having no hope and without God in the world.
Titus 3:3-7 : 3 For we were also once foolish, disobedient, deceived, serving various lusts and pleasures, living in malice and envy, hateful, and hating one another. 4 But when the kindness of God our Savior and his love toward mankind appeared, 5 not by works of righteousness, which we did ourselves, but according to his mercy, he saved us, through the washing of regeneration and renewing by the Holy Spirit, 6 whom he poured out on us richly, through Jesus Christ our Savior; 7 that, being justified by his grace, we might be made heirs according to the hope of eternal life.
Eph 2:1-3 : 1 You were made alive when you were dead in transgressions and sins, 2 in which you once walked according to the course of this world, according to the prince of the power of the air, the spirit who now works in the children of disobedience; 3 among whom we also all once lived in the lust of our flesh, doing the desires of the flesh and of the mind, and were by nature children of wrath, even as the rest.
Eph 4:18 : 18 being darkened in their understanding, alienated from the life of God, because of the ignorance that is in them, because of the hardening of their hearts;
Rom 5:9-9 : 9 Much more then, being now justified by his blood, we will be saved from God's wrath through him. 10 For if, while we were enemies, we were reconciled to God through the death of his Son, much more, being reconciled, we will be saved by his life.
1 Cor 6:9-9 : 9 Or don't you know that the unrighteous will not inherit the Kingdom of God? Don't be deceived. Neither the sexually immoral, nor idolaters, nor adulterers, nor male prostitutes, nor homosexuals, 10 nor thieves, nor covetous, nor drunkards, nor slanderers, nor extortioners, will inherit the Kingdom of God. 11 Such were some of you, but you were washed. But you were sanctified. But you were justified in the name of the Lord Jesus, and in the Spirit of our God.
Eph 2:19 : 19 So then you are no longer strangers and foreigners, but you are fellow citizens with the saints, and of the household of God,
Titus 1:15-16 : 15 To the pure, all things are pure; but to those who are defiled and unbelieving, nothing is pure; but both their mind and their conscience are defiled. 16 They profess that they know God, but by their works they deny him, being abominable, disobedient, and unfit for any good work.
Rom 1:30 : 30 backbiters, hateful to God, insolent, haughty, boastful, inventors of evil things, disobedient to parents,
Rom 8:7-8 : 7 because the mind of the flesh is hostile towards God; for it is not subject to God's law, neither indeed can it be. 8 Those who are in the flesh can't please God.
Jas 4:4 : 4 You adulterers and adulteresses, don't you know that friendship with the world is enmity with God? Whoever therefore wants to be a friend of the world makes himself an enemy of God.